The study, led by Raina Merchant, follows up research released by Penn in February that determined that language used on Twitter can closely predict cardiovascular mortality at the community level.
"A lot of people think things like Twitter are frivolous, that it's superficial, that people are tweeting about what they had for breakfast," David Asch, a researcher on the study was quoted as saying.
"Partly because people tweet from the heart - no pun intended - it may tell us a lot about people's health in important ways," Asch said.
Philadelphia County was in the 50th percentile for CDC-reported atherosclerotic heart disease (AHD) deaths versus the 60th percentile for Twitter-predicted AHD deaths.
Asch said that Penn is seeking a deeper understanding of the relationship so doctors and patients could potentially use Twitter as a cost-efficient surveillance tool for heart disease.
"One-fifth of the world's population uses Facebook and Twitter and the kinds of things that people tweet reveal something about health in a kind of interesting way."
Asch explained the study will analyse social media vernacular with an emphasis on phrases' meanings, instead of a literal take on the tweets content.
For instance, a tweet that says someone is about to have a heart attack is often an exaggeration, and would be evaluated differently than other tweets displaying a generally negative outlook.
The research will build on the correlating Twitter topics established in Penn's first study, which looked at keywords exhibiting hostility (mostly profanity), fatigue (boring, tired, sore, sleep) and interpersonal tension (hate, jealous, drama, liar). Twitter users posting this language were more likely to die from AHD.
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